TY - JOUR TI - Smoking prevalence and attributable disease burden in 195 countries and territories, 1990–2015: a systematic analysis from the Global Burden of Disease Study 2015 AU - Marissa B Reitsma AU - Nancy Fullman AU - Marie Ng AU - Joseph S Salama AU - Amanuel Alemu Abajobir AU - Kalkidan Hassen Abate AU - Cristiana Abbafati AU - Semaw Ferede Abera AU - Biju Abraham AU - Gebre Yitayih Abyu AU - Akindele O. Adebiyi AU - Ziyad Al‐Aly AU - Alicia V Aleman AU - Raghib Ali AU - Ala’a Alkerwi AU - Peter Allebeck AU - Rajaa Al‐Raddadi AU - Azmeraw T. Amare AU - Alemayehu Amberbir AU - Walid Ammar AU - Stephen M. Amrock AU - Carl Abelardo T. Antonio AU - Hamid Asayesh AU - Niguse Tadela Atnafu AU - Peter Azzopardi AU - Amitava Banerjee AU - Aleksandra Barać AU - Tonatiuh Barrientos‐Gutiérrez AU - Ana Basto‐Abreu AU - Shahrzad Bazargan‐Hejazi AU - Neeraj Bedi AU - Brent Bell AU - Aminu K. Bello AU - Isabela M. Benseñor AU - Addisu Shunu Beyene AU - Neeraj Bhala AU - Stan Biryukov AU - Kaylin Bolt AU - Hermann Brenner AU - Zahid A Butt AU - Fiorella Cavalleri AU - Kelly Cercy AU - Honglei Chen AU - Devasahayam Jesudas Christopher AU - Liliana G Ciobanu AU - Valentina Colistro AU - Mercedes Colomar AU - Leslie Cornaby AU - Xiaochen Dai AU - Solomon Abrha Damtew AU - Lalit Dandona AU - Rakhi Dandona AU - Emily Dansereau AU - Kairat Davletov AU - Anand Dayama AU - Tizta Tilahun Degfie AU - Amare Deribew AU - Samath Dhamminda Dharmaratne AU - Balem Dimtsu AU - Kerrie Doyle AU - Aman Yesuf Endries AU - Sergey Petrovich Ermakov AU - Kara Estep AU - Emerito Jose A Faraon AU - Farshad Farzadfar AU - Valery L. Feigin AU - Andrea B Feigl AU - Florian Fischer AU - Joseph Friedman AU - Tsegaye Tewelde G/hiwot AU - Seana Gall AU - Wayne Gao AU - Richard F Gillum AU - Audra L Gold AU - Sameer Vali Gopalani AU - Carolyn Gotay AU - Rahul Gupta AU - Rajeev Gupta AU - Vipin Gupta AU - Randah R Hamadeh AU - Graeme J. Hankey AU - Hilda L Harb AU - Simon I Hay AU - Masako Horino AU - Nobuyuki Horita AU - Hung Chak Ho AU - Abdullatif Husseini AU - Bogdan Vasile Ileanu AU - Farhad Islami AU - Guohong Jiang AU - Ying Jiang AU - Jost B. Jonas AU - Zubair Kabir AU - Ritul Kamal AU - Amir Kasaeian AU - Chandrasekharan Nair Kesavachandran AU - Yousef Khader AU - Ibrahim Khalil AU - Young‐Ho Khang AU - Sahil Khera PY - 2017 JO - The Lancet DO - 10.1016/s0140-6736(17)30819-x UR - https://doi.org/10.1016/s0140-6736(17)30819-x AB - BACKGROUND: The scale-up of tobacco control, especially after the adoption of the Framework Convention for Tobacco Control, is a major public health success story. Nonetheless, smoking remains a leading risk for early death and disability worldwide, and therefore continues to require sustained political commitment. The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) offers a robust platform through which global, regional, and national progress toward achieving smoking-related targets can be assessed. METHODS: We synthesised 2818 data sources with spatiotemporal Gaussian process regression and produced estimates of daily smoking prevalence by sex, age group, and year for 195 countries and territories from 1990 to 2015. We analysed 38 risk-outcome pairs to generate estimates of smoking-attributable mortality and disease burden, as measured by disability-adjusted life-years (DALYs). We then performed a cohort analysis of smoking prevalence by birth-year cohort to better understand temporal age patterns in smoking. We also did a decomposition analysis, in which we parsed out changes in all-cause smoking-attributable DALYs due to changes in population growth, population ageing, smoking prevalence, and risk-deleted DALY rates. Finally, we explored results by level of development using the Socio-demographic Index (SDI). FINDINGS: Worldwide, the age-standardised prevalence of daily smoking was 25·0% (95% uncertainty interval [UI] 24·2-25·7) for men and 5·4% (5·1-5·7) for women, representing 28·4% (25·8-31·1) and 34·4% (29·4-38·6) reductions, respectively, since 1990. A greater percentage of countries and territories achieved significant annualised rates of decline in smoking prevalence from 1990 to 2005 than in between 2005 and 2015; however, only four countries had significant annualised increases in smoking prevalence between 2005 and 2015 (Congo [Brazzaville] and Azerbaijan for men and Kuwait and Timor-Leste for women). In 2015, 11·5% of global deaths (6·4 million [95% UI 5·7-7·0 million]) were attributable to smoking worldwide, of which 52·2% took place in four countries (China, India, the USA, and Russia). Smoking was ranked among the five leading risk factors by DALYs in 109 countries and territories in 2015, rising from 88 geographies in 1990. In terms of birth cohorts, male smoking prevalence followed similar age patterns across levels of SDI, whereas much more heterogeneity was found in age patterns for female smokers by level of development. While smoking prevalence and risk-deleted DALY rates mostly decreased by sex and SDI quintile, population growth, population ageing, or a combination of both, drove rises in overall smoking-attributable DALYs in low-SDI to middle-SDI geographies between 2005 and 2015. INTERPRETATION: The pace of progress in reducing smoking prevalence has been heterogeneous across geographies, development status, and sex, and as highlighted by more recent trends, maintaining past rates of decline should not be taken for granted, especially in women and in low-SDI to middle-SDI countries. Beyond the effect of the tobacco industry and societal mores, a crucial challenge facing tobacco control initiatives is that demographic forces are poised to heighten smoking's global toll, unless progress in preventing initiation and promoting cessation can be substantially accelerated. Greater success in tobacco control is possible but requires effective, comprehensive, and adequately implemented and enforced policies, which might in turn require global and national levels of political commitment beyond what has been achieved during the past 25 years. FUNDING: Bill & Melinda Gates Foundation and Bloomberg Philanthropies. ER -