TY - JOUR TI - Bioconductor: open software development for computational biology and bioinformatics AU - Robert Gentleman AU - Vincent J. Carey AU - Douglas M. Bates AU - Ben Bolstad AU - Marcel Dettling AU - Sandrine Dudoit AU - Byron Ellis AU - Laurent Gautier AU - Yongchao Ge AU - Jeff Gentry AU - Kurt Hornik AU - Torsten Hothorn AU - Wolfgang Huber AU - Stefano M. Iacus AU - Rafael A. Irizarry AU - Friedrich Leisch AU - Cheng Li AU - Martin Maechler AU - Anthony Rossini AU - Günther Sawitzki AU - Colin A. Smith AU - Gordon K. Smyth AU - Luke Tierney AU - Jean Yang AU - Jianhua Zhang PY - 2004 JO - Genome biology DO - 10.1186/gb-2004-5-10-r80 UR - https://doi.org/10.1186/gb-2004-5-10-r80 AB - The Bioconductor project is an initiative for the collaborative creation of extensible software for computational biology and bioinformatics. The goals of the project include: fostering collaborative development and widespread use of innovative software, reducing barriers to entry into interdisciplinary scientific research, and promoting the achievement of remote reproducibility of research results. We describe details of our aims and methods, identify current challenges, compare Bioconductor to other open bioinformatics projects, and provide working examples. ER -